Structure and mechanism of the tRNA-dependent lantibiotic dehydratase NisB

Manuel A. Ortega, Yue Hao, Qi Zhang, Mark C. Walker, Wilfred A. van der Donk () and Satish K. Nair ()
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Manuel A. Ortega: University of Illinois at Urbana–Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
Yue Hao: University of Illinois at Urbana–Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
Qi Zhang: University of Illinois at Urbana–Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
Mark C. Walker: University of Illinois at Urbana–Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
Wilfred A. van der Donk: University of Illinois at Urbana–Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
Satish K. Nair: University of Illinois at Urbana–Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA

Nature, 2015, vol. 517, issue 7535, 509-512

Abstract: Structural and biochemical studies show that the biosynthesis of the food preservative nisin involves the tRNA-dependent glutamylation of serine and threonine.

Date: 2015
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DOI: 10.1038/nature13888

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