Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
Anton A. Toutov,
Wen-Bo Liu,
Kerry N. Betz,
Alexey Fedorov,
Brian M. Stoltz () and
Robert H. Grubbs ()
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Anton A. Toutov: California Institute of Technology
Wen-Bo Liu: California Institute of Technology
Kerry N. Betz: California Institute of Technology
Alexey Fedorov: California Institute of Technology
Brian M. Stoltz: California Institute of Technology
Robert H. Grubbs: California Institute of Technology
Nature, 2015, vol. 518, issue 7537, 80-84
Abstract:
Carbon–hydrogen (C–H) bond functionalization catalysed by potassium tert-butoxide, which is abundant and inexpensive, offers a direct route to the silylation of aromatic heterocycles that both obviates the need for precious metal catalysts and overcomes the limitations of previous methods.
Date: 2015
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:518:y:2015:i:7537:d:10.1038_nature14126
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DOI: 10.1038/nature14126
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