A big-hearted molecule

Michaela Kuhn ()
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Michaela Kuhn: Michaela Kuhn is at the Institute of Physiology, University of Würzburg, D-97070 Würzburg, Germany.

Nature, 2015, vol. 519, issue 7544, 416-417

Abstract: Blockade of the enzyme PDE9 prevents degradation of the molecule cyclic GMP, which has been shown to protect against heart failure. The finding indicates that PDE9 inhibition might be a drug target for treating this condition. See Letter p.472

Date: 2015
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DOI: 10.1038/nature14373

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