Clinical improvement in psoriasis with specific targeting of interleukin-23

Tamara Kopp, Elisabeth Riedl, Christine Bangert, Edward P. Bowman, Elli Greisenegger, Ann Horowitz, Harald Kittler, Wendy M. Blumenschein, Terrill K. McClanahan, Thomas Marbury, Claus Zachariae, Danlin Xu, Xiaoli Shirley Hou, Anish Mehta, Anthe S. Zandvliet, Diana Montgomery, Frank van Aarle and Sauzanne Khalilieh ()
Additional contact information
Tamara Kopp: Allergy and Infectious Diseases, University of Vienna Medical School
Elisabeth Riedl: University of Vienna Medical School
Christine Bangert: Allergy and Infectious Diseases, University of Vienna Medical School
Edward P. Bowman: Merck & Co., Inc.
Elli Greisenegger: Allergy and Infectious Diseases, University of Vienna Medical School
Ann Horowitz: Merck & Co., Inc.
Harald Kittler: University of Vienna Medical School
Wendy M. Blumenschein: Merck & Co., Inc.
Terrill K. McClanahan: Merck & Co., Inc.
Thomas Marbury: Orlando Clinical Research Center
Claus Zachariae: Gentofte Hospital, University of Copenhagen, Kildegaardsvej 28, DK-2900 Hellerup, Denmark
Danlin Xu: Merck & Co., Inc.
Xiaoli Shirley Hou: Merck & Co., Inc.
Anish Mehta: Merck & Co., Inc.
Anthe S. Zandvliet: Merck & Co., Inc.
Diana Montgomery: Merck & Co., Inc.
Frank van Aarle: Merck & Co., Inc.
Sauzanne Khalilieh: Merck & Co., Inc.

Nature, 2015, vol. 521, issue 7551, 222-226

Abstract: A proof-of-concept phase I clinical trial demonstrates that targeting interleukin (IL)-23 with an antibody that binds to the p19 subunit leads to clinical improvement of disease in patients with moderate to severe psoriasis.

Date: 2015
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/nature14175 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:521:y:2015:i:7551:d:10.1038_nature14175

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature14175

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().