Atomic structure of anthrax protective antigen pore elucidates toxin translocation

Jiansen Jiang, Bradley L. Pentelute, R. John Collier and Z. Hong Zhou ()
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Jiansen Jiang: Immunology and Molecular Genetics, University of California
Bradley L. Pentelute: Massachusetts Institute of Technology
R. John Collier: Harvard Medical School
Z. Hong Zhou: Immunology and Molecular Genetics, University of California

Nature, 2015, vol. 521, issue 7553, 545-549

Abstract: Cryo-electron microscopy determination of anthrax toxin protective antigen pore structure at a resolution of 2.9 Å, revealing the catalytic Φ-clamp and the membrane-spanning translocation channel.

Date: 2015
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DOI: 10.1038/nature14247

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