Precise control of localized signals

Vuk Stambolic ()
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Vuk Stambolic: Vuk Stambolic is at the Princess Margaret Cancer Centre, University Health Network, University of Toronto, Toronto M5G 1L7, Canada.

Nature, 2015, vol. 522, issue 7554, 38-40

Abstract: The tumour-suppressor protein PTEN is mostly found in the cell cytoplasm, tethered to endosome vesicles. This localization regulates the enzyme's activity towards specific lipids and influences its control of cell growth.

Date: 2015
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DOI: 10.1038/nature14531

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