The micronucleus gets its big break

Kristin A. Knouse and Angelika Amon ()
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Kristin A. Knouse: Kristin A. Knouse and Angelika Amon are at the Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Angelika Amon: Kristin A. Knouse and Angelika Amon are at the Koch Institute for Integrative Cancer Research, Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Nature, 2015, vol. 522, issue 7555, 162-163

Abstract: Extensive chromosomal rearrangement – chromothripsis – is seen in several cancers. Imaging and sequencing of single cells shows that this phenomenon can occur inside cellular anomalies known as micronuclei. See Article p.179

Date: 2015
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DOI: 10.1038/nature14528

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