The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth

Ditte S. Andersen, Julien Colombani (), Valentina Palmerini, Krittalak Chakrabandhu, Emilie Boone, Michael Röthlisberger, Janine Toggweiler, Konrad Basler, Marina Mapelli, Anne-Odile Hueber and Pierre Léopold ()
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Ditte S. Andersen: University of Nice-Sophia Antipolis, Institute of Biology Valrose
Julien Colombani: University of Nice-Sophia Antipolis, Institute of Biology Valrose
Valentina Palmerini: European Institute of Oncology
Krittalak Chakrabandhu: University of Nice-Sophia Antipolis, Institute of Biology Valrose
Emilie Boone: University of Nice-Sophia Antipolis, Institute of Biology Valrose
Michael Röthlisberger: Institute of Molecular Life Sciences, University of Zurich
Janine Toggweiler: Institute of Molecular Life Sciences, University of Zurich
Konrad Basler: Institute of Molecular Life Sciences, University of Zurich
Marina Mapelli: European Institute of Oncology
Anne-Odile Hueber: University of Nice-Sophia Antipolis, Institute of Biology Valrose
Pierre Léopold: University of Nice-Sophia Antipolis, Institute of Biology Valrose

Nature, 2015, vol. 522, issue 7557, 482-486

Abstract: Cell polarity is an important feature of many tissues and is often disrupted in cancer; the TNF receptor Grindelwald is now shown to have an important role in coordinating cell polarity and neoplastic growth in a Drosophila model.

Date: 2015
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DOI: 10.1038/nature14298

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