Evolved protection against human prions

Glenn Telling ()
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Glenn Telling: Glenn Telling is at the Prion Research Center, Colorado State University, Fort Collins, Colorado 80525, USA.

Nature, 2015, vol. 522, issue 7557, 423-424

Abstract: A genetic variant of PrP, the protein that forms prions, confers protection against the human prion disease kuru by inhibiting the conversion of functional isoforms to the abnormal, disease-causing conformation. See Letter p.478

Date: 2015
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DOI: 10.1038/nature14534

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