MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis

Cheryl M. Koh, Marco Bezzi, Diana H. P. Low, Wei Xia Ang, Shun Xie Teo, Florence P. H. Gay, Muthafar Al-Haddawi, Soo Yong Tan, Motomi Osato, Arianna Sabò, Bruno Amati, Keng Boon Wee and Ernesto Guccione ()
Additional contact information
Cheryl M. Koh: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Marco Bezzi: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Diana H. P. Low: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Wei Xia Ang: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Shun Xie Teo: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Florence P. H. Gay: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Muthafar Al-Haddawi: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Soo Yong Tan: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)
Motomi Osato: Cancer Science Institute of Singapore (CSI), National University of Singapore
Arianna Sabò: Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia (IIT)
Bruno Amati: Center for Genomic Science of IIT@SEMM, Fondazione Istituto Italiano di Tecnologia (IIT)
Keng Boon Wee: Institute of High Performance Computing (IHPC), A*STAR (Agency for Science, Technology and Research), Connexis
Ernesto Guccione: Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research)

Nature, 2015, vol. 523, issue 7558, 96-100

Abstract: The critical effectors of MYC overexpression during lymphomagenesis in transgenic mice are defined.

Date: 2015
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DOI: 10.1038/nature14351

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