Spatiotemporal control of a novel synaptic organizer molecule

Kelly Howell (), John G. White and Oliver Hobert ()
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Kelly Howell: Howard Hughes Medical Institute, Columbia University Medical Center
John G. White: MRC Laboratory of Molecular Biology
Oliver Hobert: Howard Hughes Medical Institute, Columbia University Medical Center

Nature, 2015, vol. 523, issue 7558, 83-87

Abstract: Neuronal synapses need to be formed at the right time and the right place during nervous system development; here, three gene-regulatory factors (the UNC-30, LIN-14 and UNC-55 DNA-binding proteins) are shown to operate in an intersectional manner to control the expression of a novel synaptic organizer molecule, OIG-1.

Date: 2015
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DOI: 10.1038/nature14545

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