Single-cell chromatin accessibility reveals principles of regulatory variation

Jason D. Buenrostro, Beijing Wu, Ulrike M. Litzenburger, Dave Ruff, Michael L. Gonzales, Michael P. Snyder, Howard Y. Chang () and William J. Greenleaf ()
Additional contact information
Jason D. Buenrostro: Stanford University School of Medicine
Beijing Wu: Stanford University School of Medicine
Ulrike M. Litzenburger: Program in Epithelial Biology and the Howard Hughes Medical Institute, Stanford University School of Medicine
Dave Ruff: Fluidigm Corporation
Michael L. Gonzales: Fluidigm Corporation
Michael P. Snyder: Stanford University School of Medicine
Howard Y. Chang: Program in Epithelial Biology and the Howard Hughes Medical Institute, Stanford University School of Medicine
William J. Greenleaf: Stanford University School of Medicine

Nature, 2015, vol. 523, issue 7561, 486-490

Abstract: A single-cell method for probing genome-wide chromatin accessibility has been developed; the results provide insight into the relationship between cell-to-cell variation associated with specific trans-factors and cis-elements, as well insights into the relationship between chromatin accessibility and three-dimensional genome organization.

Date: 2015
References: Add references at CitEc
Citations: View citations in EconPapers (24)

Downloads: (external link)
https://www.nature.com/articles/nature14590 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:523:y:2015:i:7561:d:10.1038_nature14590

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature14590

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().