Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic

Etienne Simon-Loriere (), Ousmane Faye, Oumar Faye, Lamine Koivogui, Nfaly Magassouba, Sakoba Keita, Jean-Michel Thiberge, Laure Diancourt, Christiane Bouchier, Matthias Vandenbogaert, Valérie Caro, Gamou Fall, Jan P. Buchmann, Christan B. Matranga, Pardis C. Sabeti, Jean-Claude Manuguerra, Edward C. Holmes () and Amadou A. Sall ()
Additional contact information
Etienne Simon-Loriere: Institut Pasteur, Functional Genetics of Infectious Diseases Unit
Ousmane Faye: Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit
Oumar Faye: Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit
Lamine Koivogui: Institut National de Santé Publique de Guinée
Nfaly Magassouba: Projet de fièvres hémorragiques de Guinée, Université Gamal Abdel Nasser
Sakoba Keita: Ministry of Health
Jean-Michel Thiberge: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence
Laure Diancourt: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence
Christiane Bouchier: Institut Pasteur, Genomic platform
Matthias Vandenbogaert: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence
Valérie Caro: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence
Gamou Fall: Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit
Jan P. Buchmann: Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney
Christan B. Matranga: Broad Institute
Pardis C. Sabeti: Broad Institute
Jean-Claude Manuguerra: Institut Pasteur, Unité Environnement et Risques Infectieux, Cellule d’Intervention Biologique d’Urgence
Edward C. Holmes: Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, School of Biological Sciences and Sydney Medical School, The University of Sydney
Amadou A. Sall: Institut Pasteur de Dakar, Arbovirus and Viral Hemorrhagic Fever Unit

Nature, 2015, vol. 524, issue 7563, 102-104

Abstract: An analysis of 85 Ebola virus sequences collected in Guinea from July to November 2014 provides insight into the evolution of the Ebola virus responsible for the epidemic in West Africa; the results show sustained transmission of three co-circulating lineages, each defined by multiple mutations.

Date: 2015
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DOI: 10.1038/nature14612

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