Salvaging the genome
Sharanya Sivanand and
Kathryn E. Wellen ()
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Sharanya Sivanand: Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Kathryn E. Wellen: Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Nature, 2015, vol. 524, issue 7563, 40-41
Abstract:
Overexpression of the enzyme cytidine deaminase allows the incorporation of abnormally modified nucleotides into DNA, leading to cell death. This discovery might point the way to treating some cancers. See Letter p.114
Date: 2015
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DOI: 10.1038/nature14638
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