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Bumps in the road to therapeutic antibodies

Leslie Goo and Theodore C. Pierson ()
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Leslie Goo: Leslie Goo and Theodore C. Pierson are in the Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
Theodore C. Pierson: Leslie Goo and Theodore C. Pierson are in the Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature, 2015, vol. 524, issue 7565, 295-296

Abstract: A human antibody against dengue virus serotype 2 has been shown to protect mice against disease. Structures of the antibody bound to the virus illuminate how it binds different viral forms to prevent virus entry into cells.

Date: 2015
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DOI: 10.1038/524295a

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