Hypoxia response becomes crystal clear
Ronen Marmorstein () and
M. Celeste Simon ()
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Ronen Marmorstein: Ronen Marmorstein is in the Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.
M. Celeste Simon: M. Celeste Simon is in the Abramson Family Cancer Research Institute, Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania 19104, USA.
Nature, 2015, vol. 524, issue 7565, 298-299
Abstract:
The crystal structures of two proteins that respond to reduced tissue oxygen levels — hypoxia-inducible factors — provide insight into their function and reveal sites for rational drug design. See Article p.303
Date: 2015
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DOI: 10.1038/nature14641
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