Unequal opportunity during class switching

Javier M. Di Noia ()
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Javier M. Di Noia: Université de Montréal, Montreal, Quebec H2W 1R7, Canada.

Nature, 2015, vol. 525, issue 7567, 44-45

Abstract: The DNA breakage-and-repair mechanism that generates antibodies of different classes has, in theory, a 50% chance of occurring correctly. But this recombination turns out to be heavily biased towards productive events. See Letter p.134

Date: 2015
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DOI: 10.1038/nature15209

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