Allosteric receptor activation by the plant peptide hormone phytosulfokine

Jizong Wang, Hongju Li, Zhifu Han, Heqiao Zhang, Tong Wang, Guangzhong Lin, Junbiao Chang, Weicai Yang () and Jijie Chai ()
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Jizong Wang: Ministry of Education Key Laboratory of Protein Science, Center for Structural Biology, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University
Hongju Li: State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Zhifu Han: Ministry of Education Key Laboratory of Protein Science, Center for Structural Biology, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University
Heqiao Zhang: Ministry of Education Key Laboratory of Protein Science, Center for Structural Biology, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University
Tong Wang: State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Guangzhong Lin: Ministry of Education Key Laboratory of Protein Science, Center for Structural Biology, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University
Junbiao Chang: School of Chemistry and Molecular Engineering, Zhengzhou University
Weicai Yang: State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Jijie Chai: Ministry of Education Key Laboratory of Protein Science, Center for Structural Biology, School of Life Sciences, Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University

Nature, 2015, vol. 525, issue 7568, 265-268

Abstract: Insights derived from the crystal structures of the extracellular domain of PSKR, the receptor for the plant hormone phytosulfokine (PSK) that affects plant growth and development, reveal that PSK interacts with PSKR and enhances PSKR interaction with its co-receptor SERK allosterically.

Date: 2015
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DOI: 10.1038/nature14858

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