A sexually dimorphic hypothalamic circuit controls maternal care and oxytocin secretion

Niv Scott, Matthias Prigge, Ofer Yizhar () and Tali Kimchi ()
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Niv Scott: Weizmann Institute of Science
Matthias Prigge: Weizmann Institute of Science
Ofer Yizhar: Weizmann Institute of Science
Tali Kimchi: Weizmann Institute of Science

Nature, 2015, vol. 525, issue 7570, 519-522

Abstract: Sexual dimorphism in neuronal circuits is proposed to underlie sex differences in behaviour, such as virgin female mice acting maternally toward alien pups, while males ignore or attack them; here the authors show that specific tyrosine hydroxylase-expressing neurons in the hypothalamus are more numerous in mothers than in virgin females and males, and that they control parental behaviour in a sex-specific manner.

Date: 2015
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DOI: 10.1038/nature15378

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