Antiviral action countered by Nef

Christopher Aiken ()
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Christopher Aiken: Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-2363, USA.

Nature, 2015, vol. 526, issue 7572, 202-203

Abstract: The HIV protein Nef is a viral 'Swiss army knife' with many functions. New work now shows how Nef increases infectivity — by inhibiting two of the host cell's antiviral proteins, SERINC3 and SERINC5. See Articles p.212 & p.218

Date: 2015
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DOI: 10.1038/nature15637

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