Encoding of action by the Purkinje cells of the cerebellum

David J. Herzfeld (), Yoshiko Kojima, Robijanto Soetedjo and Reza Shadmehr ()
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David J. Herzfeld: Laboratory for Computational Motor Control, Johns Hopkins University School of Medicine
Yoshiko Kojima: Washington National Primate Center, University of Washington
Robijanto Soetedjo: Washington National Primate Center, University of Washington
Reza Shadmehr: Laboratory for Computational Motor Control, Johns Hopkins University School of Medicine

Nature, 2015, vol. 526, issue 7573, 439-442

Abstract: Recording from Purkinje cells in monkeys, this study found that the combined simple-spike responses of bursting and pausing Purkinje cells, but not either population alone, predicted the real-time speed of saccades; moreover, when Purkinje cells were organized according to their complex-spike field, the population responses encoded both speed and direction of the eye during saccades via a gain field.

Date: 2015
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DOI: 10.1038/nature15693

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