Caspase target drives pyroptosis

Petr Broz ()
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Petr Broz: Petr Broz is at the Biozentrum, University of Basel, CH-4056 Basel, Switzerland.

Nature, 2015, vol. 526, issue 7575, 642-643

Abstract: Inflammatory caspase proteins help to control pathogen replication by triggering pyroptotic cell death. It now emerges that cleavage of the caspase substrate gasdermin D is sufficient to induce pyroptosis. See Articles p.660 & p.666

Date: 2015
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DOI: 10.1038/nature15632

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