Structure of a eukaryotic SWEET transporter in a homotrimeric complex

Yuyong Tao, Lily S. Cheung, Shuo Li, Joon-Seob Eom, Li-Qing Chen, Yan Xu, Kay Perry, Wolf B. Frommer and Liang Feng ()
Additional contact information
Yuyong Tao: 279 Campus Drive, Stanford University School of Medicine
Lily S. Cheung: Carnegie Institution for Science
Shuo Li: 279 Campus Drive, Stanford University School of Medicine
Joon-Seob Eom: Carnegie Institution for Science
Li-Qing Chen: Carnegie Institution for Science
Yan Xu: 279 Campus Drive, Stanford University School of Medicine
Kay Perry: NE-CAT and Dep. of Chemistry and Chemical Biology, Cornell University
Wolf B. Frommer: Carnegie Institution for Science
Liang Feng: 279 Campus Drive, Stanford University School of Medicine

Nature, 2015, vol. 527, issue 7577, 259-263

Abstract: The X-ray crystal structure is presented of a seven-transmembrane eukaryotic SWEET glucose transporter, revealing the link between seven-transmembrane eukaryotic SWEETs and their three-transmembrane bacterial homologues and providing insight into eukaryotic sugar transport mechanisms.

Date: 2015
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DOI: 10.1038/nature15391

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