Foreign DNA capture during CRISPR–Cas adaptive immunity

James K. Nuñez, Lucas B. Harrington, Philip J. Kranzusch, Alan N. Engelman and Jennifer A. Doudna ()
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James K. Nuñez: University of California, Berkeley
Lucas B. Harrington: University of California, Berkeley
Philip J. Kranzusch: University of California, Berkeley
Alan N. Engelman: Dana-Farber Cancer Institute
Jennifer A. Doudna: University of California, Berkeley

Nature, 2015, vol. 527, issue 7579, 535-538

Abstract: The structure of the Cas1–Cas2 complex bound to a protospacer sequence illustrates how foreign DNA is captured and measured by bacterial proteins in preparation for integration into CRISPR loci.

Date: 2015
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DOI: 10.1038/nature15760

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