In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus

Xing Zhang, Ke Ding, Xuekui Yu, Winston Chang, Jingchen Sun () and Z. Hong Zhou ()
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Xing Zhang: California Nanosystems Institute, University of California
Ke Ding: Immunology and Molecular Genetics, University of California
Xuekui Yu: Immunology and Molecular Genetics, University of California
Winston Chang: California Nanosystems Institute, University of California
Jingchen Sun: Immunology and Molecular Genetics, University of California
Z. Hong Zhou: California Nanosystems Institute, University of California

Nature, 2015, vol. 527, issue 7579, 531-534

Abstract: This study visualizes the interior of a dsRNA virus using cryo-electron microscopy, revealing the organization of the genome of cytoplasmic polyhedrosis virus together with its transcriptional enzyme complex in both quiescent and transcribing states.

Date: 2015
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DOI: 10.1038/nature15767

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