A mechanism of viral immune evasion revealed by cryo-EM analysis of the TAP transporter

Michael L. Oldham, Richard K. Hite, Alanna M. Steffen, Ermelinda Damko, Zongli Li, Thomas Walz and Jue Chen ()
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Michael L. Oldham: The Rockefeller University
Richard K. Hite: The Rockefeller University
Alanna M. Steffen: Howard Hughes Medical Institute
Ermelinda Damko: The Rockefeller University
Zongli Li: Howard Hughes Medical Institute
Thomas Walz: The Rockefeller University
Jue Chen: The Rockefeller University

Nature, 2016, vol. 529, issue 7587, 537-540

Abstract: The cryo-electron microscopy structure of human TAP transporter, a peptide transporter central to MHC class I antigen presentation and cellular immunity, in complex with the herpes simplex virus protein ICP47.

Date: 2016
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DOI: 10.1038/nature16506

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