Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

Henner F. Farin (), Ingrid Jordens, Mohammed H. Mosa, Onur Basak, Jeroen Korving, Daniele V. F. Tauriello, Karin de Punder, Stephane Angers, Peter J. Peters, Madelon M. Maurice and Hans Clevers ()
Additional contact information
Henner F. Farin: Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht
Ingrid Jordens: Center for Molecular Medicine, University Medical Center Utrecht
Mohammed H. Mosa: German Cancer Consortium (DKTK)
Onur Basak: Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht
Jeroen Korving: Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht
Daniele V. F. Tauriello: Center for Molecular Medicine, University Medical Center Utrecht
Karin de Punder: The Maastricht Multimodal Molecular Imaging institute, Maastricht University
Stephane Angers: Leslie Dan Faculty of Pharmacy, University of Toronto
Peter J. Peters: The Maastricht Multimodal Molecular Imaging institute, Maastricht University
Madelon M. Maurice: Center for Molecular Medicine, University Medical Center Utrecht
Hans Clevers: Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht

Nature, 2016, vol. 530, issue 7590, 340-343

Abstract: Generation of an epitope-tagged, functional Wnt3 knock-in allele, the signal produced by Paneth cells to regulate intestinal stem cells.

Date: 2016
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DOI: 10.1038/nature16937

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