Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function

Allison Ballandras-Colas, Monica Brown, Nicola J. Cook, Tamaria G. Dewdney, Borries Demeler, Peter Cherepanov, Dmitry Lyumkis () and Alan N. Engelman ()
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Allison Ballandras-Colas: Harvard Medical School
Monica Brown: Laboratory of Genetics and Helmsley Center for Genomic Medicine, The Salk Institute for Biological Studies
Nicola J. Cook: Clare Hall Laboratories, The Francis Crick Institute, Blanche Lane
Tamaria G. Dewdney: Harvard Medical School
Borries Demeler: The University of Texas Health Science Center at San Antonio
Peter Cherepanov: Clare Hall Laboratories, The Francis Crick Institute, Blanche Lane
Dmitry Lyumkis: Laboratory of Genetics and Helmsley Center for Genomic Medicine, The Salk Institute for Biological Studies
Alan N. Engelman: Harvard Medical School

Nature, 2016, vol. 530, issue 7590, 358-361

Abstract: An unexpected octameric integrase architecture for the betaretrovirus mouse mammary tumour virus intasome.

Date: 2016
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DOI: 10.1038/nature16955

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