Derivation and differentiation of haploid human embryonic stem cells

Ido Sagi, Gloryn Chia, Tamar Golan-Lev, Mordecai Peretz, Uri Weissbein, Lina Sui, Mark V. Sauer, Ofra Yanuka, Dieter Egli () and Nissim Benvenisty ()
Additional contact information
Ido Sagi: The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University
Gloryn Chia: Columbia University
Tamar Golan-Lev: The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University
Mordecai Peretz: The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University
Uri Weissbein: The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University
Lina Sui: Columbia University
Mark V. Sauer: Center for Women’s Reproductive Care, College of Physicians and Surgeons, Columbia University
Ofra Yanuka: The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University
Dieter Egli: Columbia University
Nissim Benvenisty: The Azrieli Center for Stem Cells and Genetic Research, Silberman Institute of Life Sciences, The Hebrew University

Nature, 2016, vol. 532, issue 7597, 107-111

Abstract: Haploid human embryonic stem cells have been derived from haploid oocytes, the cells maintain a normal haploid karyotype as pluripotent cells and, unexpectedly, as differentiated cells — loss-of-function genetic screens previously performed with haploid embryonic stem cells in mice can now be performed in humans.

Date: 2016
References: Add references at CitEc
Citations: View citations in EconPapers (1)

Downloads: (external link)
https://www.nature.com/articles/nature17408 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:532:y:2016:i:7597:d:10.1038_nature17408

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature17408

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().