Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

Katherine C. Verbist, Cliff S. Guy, Sandra Milasta, Swantje Liedmann, Marcin M. Kamiński, Ruoning Wang and Douglas R. Green ()
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Katherine C. Verbist: St. Jude Children’s Research Hospital
Cliff S. Guy: St. Jude Children’s Research Hospital
Sandra Milasta: St. Jude Children’s Research Hospital
Swantje Liedmann: St. Jude Children’s Research Hospital
Marcin M. Kamiński: St. Jude Children’s Research Hospital
Ruoning Wang: Center for Childhood Cancer and Blood Disease, The Research Institute at Nationwide Children’s Hospital
Douglas R. Green: St. Jude Children’s Research Hospital

Nature, 2016, vol. 532, issue 7599, 389-393

Abstract: The asymmetric distribution of mTORC1 and c-Myc in the first division of daughter cells of activated CD8 T cells affects the proliferation, metabolism and differentiation potential of their progeny.

Date: 2016
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DOI: 10.1038/nature17442

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