EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells

Jianhua Li, Erick Lu, Tangsheng Yi and Jason G. Cyster ()
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Jianhua Li: University of California, San Francisco
Erick Lu: University of California, San Francisco
Tangsheng Yi: University of California, San Francisco
Jason G. Cyster: University of California, San Francisco

Nature, 2016, vol. 533, issue 7601, 110-114

Abstract: The differentiation of T follicular helper cells requires the G-protein-coupled receptor Ebi2 as well as the interaction with CD25-producing dendritic cells that quench T-cell-derived interleukin-2.

Date: 2016
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DOI: 10.1038/nature17947

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