Diverse roles of assembly factors revealed by structures of late nuclear pre-60S ribosomes

Shan Wu, Beril Tutuncuoglu, Kaige Yan, Hailey Brown, Yixiao Zhang, Dan Tan, Michael Gamalinda, Yi Yuan, Zhifei Li, Jelena Jakovljevic, Chengying Ma, Jianlin Lei, Meng-Qiu Dong, John L. Woolford () and Ning Gao ()
Additional contact information
Shan Wu: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University
Beril Tutuncuoglu: Carnegie Mellon University
Kaige Yan: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University
Hailey Brown: Carnegie Mellon University
Yixiao Zhang: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University
Dan Tan: Graduate Program in Chinese Academy of Medical Sciences and Peking Union Medical College
Michael Gamalinda: Carnegie Mellon University
Yi Yuan: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University
Zhifei Li: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University
Jelena Jakovljevic: Carnegie Mellon University
Chengying Ma: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University
Jianlin Lei: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University
Meng-Qiu Dong: Graduate Program in Chinese Academy of Medical Sciences and Peking Union Medical College
John L. Woolford: Carnegie Mellon University
Ning Gao: Ministry of Education Key Laboratory of Protein Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University

Nature, 2016, vol. 534, issue 7605, 133-137

Abstract: The cryo-electron microscopy structures of yeast nucleoplasmic pre-60S ribosomal particles give insight into the function of multiple assembly factors in ribosome biogenesis.

Date: 2016
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DOI: 10.1038/nature17942

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