Concerted nucleophilic aromatic substitution with 19F− and 18F−
Constanze N. Neumann,
Jacob M. Hooker and
Tobias Ritter ()
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Constanze N. Neumann: Harvard University
Jacob M. Hooker: Massachusetts General Hospital
Tobias Ritter: Harvard University
Nature, 2016, vol. 534, issue 7607, 369-373
Abstract:
Nucleophilic aromatic substitution (SNAr) is the most commonly used method to generate arenes that contain 18F for use in PET imaging; here, an unusual concerted SNAr reaction is presented that is not limited to electron-poor arenes.
Date: 2016
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Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:534:y:2016:i:7607:d:10.1038_nature17667
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DOI: 10.1038/nature17667
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