The bacterial DnaA-trio replication origin element specifies single-stranded DNA initiator binding

Tomas T. Richardson, Omar Harran and Heath Murray ()
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Tomas T. Richardson: Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne NE2 4AX
Omar Harran: Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne NE2 4AX
Heath Murray: Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne NE2 4AX

Nature, 2016, vol. 534, issue 7607, 412-416

Abstract: The bacterial chromosome replication origin contains an indispensable element composed of a repeating trinucleotide motif, termed the DnaA-trio, that stabilizes DnaA binding on single-stranded DNA.

Date: 2016
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DOI: 10.1038/nature17962

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