AMPK–SKP2–CARM1 signalling cascade in transcriptional regulation of autophagy

Hi-Jai R. Shin, Hyunkyung Kim, Sungryong Oh, Jun-Gi Lee, Minjung Kee, Hyun-Jeong Ko, Mi-Na Kweon, Kyoung-Jae Won and Sung Hee Baek ()
Additional contact information
Hi-Jai R. Shin: Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University
Hyunkyung Kim: Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University
Sungryong Oh: Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University
Jun-Gi Lee: Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University
Minjung Kee: Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University
Hyun-Jeong Ko: Laboratory of Microbiology and Immunology, College of Pharmacy, Kangwon National University
Mi-Na Kweon: Mucosal Immunology Laboratory, University of Ulsan College of Medicine, Asan Medical Center
Kyoung-Jae Won: The Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania
Sung Hee Baek: Creative Research Initiatives Center for Chromatin Dynamics, School of Biological Sciences, Seoul National University

Nature, 2016, vol. 534, issue 7608, 553-557

Abstract: An investigation into the nuclear events involved in autophagy regulation identifies the histone arginine methyltransferase CARM1 as a transcriptional co-activator of transcription factor TFEB; CARM1 levels are decreased by the SKP2-containing E3 ubiquitin ligase and increased during autophagy induction after nutrient starvation.

Date: 2016
References: Add references at CitEc
Citations: View citations in EconPapers (3)

Downloads: (external link)
https://www.nature.com/articles/nature18014 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:534:y:2016:i:7608:d:10.1038_nature18014

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature18014

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().