The TORC1 pathway to protein destruction

Lynne Chantranupong () and David M. Sabatini ()
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Lynne Chantranupong: Lynne Chantranupong and David M. Sabatini are at the Whitehead Institute, Cambridge, Massachusetts 02142, USA.
David M. Sabatini: Lynne Chantranupong and David M. Sabatini are at the Whitehead Institute, Cambridge, Massachusetts 02142, USA.

Nature, 2016, vol. 536, issue 7615, 155-156

Abstract: A study of the proteasome — a protein-degradation complex — reveals an evolutionarily conserved pathway that acts through the protein kinase TORC1 to adjust proteasome levels in response to cellular needs. See Letter p.184

Date: 2016
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DOI: 10.1038/nature18919

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