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Reconstruction of bacterial transcription-coupled repair at single-molecule resolution

Jun Fan, Mathieu Leroux-Coyau, Nigel J. Savery and Terence R. Strick ()
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Jun Fan: Institut Jacques Monod, CNRS, UMR7592, University Paris Diderot
Mathieu Leroux-Coyau: Institut Jacques Monod, CNRS, UMR7592, University Paris Diderot
Nigel J. Savery: DNA-Protein Interactions Unit, School of Biochemistry, University of Bristol
Terence R. Strick: Institut Jacques Monod, CNRS, UMR7592, University Paris Diderot

Nature, 2016, vol. 536, issue 7615, 234-237

Abstract: Single-molecule assays show that the recruitment of UvrA and UvrAB to Mfd–RNA polymerase complex formed on a DNA lesion arrests the translocating complex and causes its dissolution.

Date: 2016
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DOI: 10.1038/nature19080

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