Vaccine protection against Zika virus from Brazil

Rafael A. Larocca, Peter Abbink, Jean Pierre S. Peron, Paolo M. de A. Zanotto, M. Justin Iampietro, Alexander Badamchi-Zadeh, Michael Boyd, David Ng’ang’a, Marinela Kirilova, Ramya Nityanandam, Noe B. Mercado, Zhenfeng Li, Edward T. Moseley, Christine A. Bricault, Erica N. Borducchi, Patricia B. Giglio, David Jetton, George Neubauer, Joseph P. Nkolola, Lori F. Maxfield, Rafael A. De La Barrera, Richard G. Jarman, Kenneth H. Eckels, Nelson L. Michael, Stephen J. Thomas and Dan H. Barouch ()
Additional contact information
Rafael A. Larocca: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Peter Abbink: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Jean Pierre S. Peron: University of São Paulo
Paolo M. de A. Zanotto: University of São Paulo
M. Justin Iampietro: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Alexander Badamchi-Zadeh: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Michael Boyd: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
David Ng’ang’a: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Marinela Kirilova: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Ramya Nityanandam: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Noe B. Mercado: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Zhenfeng Li: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Edward T. Moseley: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Christine A. Bricault: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Erica N. Borducchi: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Patricia B. Giglio: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
David Jetton: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
George Neubauer: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Joseph P. Nkolola: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Lori F. Maxfield: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School
Rafael A. De La Barrera: Walter Reed Army Institute of Research
Richard G. Jarman: Walter Reed Army Institute of Research
Kenneth H. Eckels: Walter Reed Army Institute of Research
Nelson L. Michael: Walter Reed Army Institute of Research
Stephen J. Thomas: Walter Reed Army Institute of Research
Dan H. Barouch: Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School

Nature, 2016, vol. 536, issue 7617, 474-478

Abstract: The authors test several candidate vaccines for Zika virus in mouse models and show that single-shot DNA vaccines and inactivated virus vaccines provide complete protection against Zika virus isolates from Brazil and Puerto Rico.

Date: 2016
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DOI: 10.1038/nature18952

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