Digits and fin rays share common developmental histories

Tetsuya Nakamura, Andrew R. Gehrke, Justin Lemberg, Julie Szymaszek and Neil H. Shubin ()
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Tetsuya Nakamura: University of Chicago
Andrew R. Gehrke: University of Chicago
Justin Lemberg: University of Chicago
Julie Szymaszek: University of Chicago
Neil H. Shubin: University of Chicago

Nature, 2016, vol. 537, issue 7619, 225-228

Abstract: Hoxa- and Hoxd-deficient zebrafish generated using Crispr/Cas with fate mapping have reduced fin rays and increased endochondral elements, establishing homology between the developmental programs that create fin rays and the wrists and digits of mammals.

Date: 2016
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DOI: 10.1038/nature19322

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