Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system

Sung Hoon Cho, Ariel L. Raybuck, Kristy Stengel, Mei Wei, Thomas C. Beck, Emmanuel Volanakis, James W. Thomas, Scott Hiebert, Volker H. Haase and Mark R. Boothby ()
Additional contact information
Sung Hoon Cho: Microbiology and Immunology, Vanderbilt University
Ariel L. Raybuck: Microbiology and Immunology, Vanderbilt University
Kristy Stengel: Vanderbilt University
Mei Wei: Microbiology and Immunology, Vanderbilt University
Thomas C. Beck: Microbiology and Immunology, Vanderbilt University
Emmanuel Volanakis: Vanderbilt University
James W. Thomas: Microbiology and Immunology, Vanderbilt University
Scott Hiebert: Vanderbilt University
Volker H. Haase: Vanderbilt University
Mark R. Boothby: Microbiology and Immunology, Vanderbilt University

Nature, 2016, vol. 537, issue 7619, 234-238

Abstract: Hypoxia in germinal centres regulates B cell class switching via its effects on mTOR complex 1 and activation-induced cytosine deaminase activity.

Date: 2016
References: Add references at CitEc
Citations: View citations in EconPapers (7)

Downloads: (external link)
https://www.nature.com/articles/nature19334 Abstract (text/html)
Access to the full text of the articles in this series is restricted.

Related works:
This item may be available elsewhere in EconPapers: Search for items with the same title.

Export reference: BibTeX RIS (EndNote, ProCite, RefMan) HTML/Text

Persistent link: https://EconPapers.repec.org/RePEc:nat:nature:v:537:y:2016:i:7619:d:10.1038_nature19334

Ordering information: This journal article can be ordered from
https://www.nature.com/

DOI: 10.1038/nature19334

Access Statistics for this article

Nature is currently edited by Magdalena Skipper

More articles in Nature from Nature
Bibliographic data for series maintained by Sonal Shukla () and Springer Nature Abstracting and Indexing ().