Rewriting yeast central carbon metabolism for industrial isoprenoid production

Adam L. Meadows, Kristy M. Hawkins, Yoseph Tsegaye, Eugene Antipov, Youngnyun Kim, Lauren Raetz, Robert H. Dahl, Anna Tai, Tina Mahatdejkul-Meadows, Lan Xu, Lishan Zhao, Madhukar S. Dasika, Abhishek Murarka, Jacob Lenihan, Diana Eng, Joshua S. Leng, Chi-Li Liu, Jared W. Wenger, Hanxiao Jiang, Lily Chao, Patrick Westfall, Jefferson Lai, Savita Ganesan, Peter Jackson, Robert Mans, Darren Platt, Christopher D. Reeves, Poonam R. Saija, Gale Wichmann, Victor F. Holmes, Kirsten Benjamin, Paul W. Hill, Timothy S. Gardner and Annie E. Tsong ()
Additional contact information
Adam L. Meadows: Amyris
Kristy M. Hawkins: Amyris
Yoseph Tsegaye: Amyris
Eugene Antipov: Amyris
Youngnyun Kim: Amyris
Lauren Raetz: Amyris
Robert H. Dahl: Amyris
Anna Tai: Amyris
Tina Mahatdejkul-Meadows: Amyris
Lan Xu: Amyris
Lishan Zhao: Amyris
Madhukar S. Dasika: Amyris
Abhishek Murarka: Amyris
Jacob Lenihan: Amyris
Diana Eng: Amyris
Joshua S. Leng: Amyris
Chi-Li Liu: Amyris
Jared W. Wenger: Amyris
Hanxiao Jiang: Amyris
Lily Chao: Amyris
Patrick Westfall: Amyris
Jefferson Lai: Amyris
Savita Ganesan: Amyris
Peter Jackson: Amyris
Robert Mans: Amyris
Darren Platt: Amyris
Christopher D. Reeves: Amyris
Poonam R. Saija: Amyris
Gale Wichmann: Amyris
Victor F. Holmes: Amyris
Kirsten Benjamin: Amyris
Paul W. Hill: Amyris
Timothy S. Gardner: Amyris
Annie E. Tsong: Amyris

Nature, 2016, vol. 537, issue 7622, 694-697

Abstract: Yeast central carbon metabolism has been engineered to achieve a more efficient isoprenoid biosynthesis pathway, an advance that brings commodity-scale production of such compounds a step closer.

Date: 2016
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DOI: 10.1038/nature19769

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