The lipolysis pathway sustains normal and transformed stem cells in adult Drosophila

Shree Ram Singh, Xiankun Zeng, Jiangsha Zhao, Ying Liu, Gerald Hou, Hanhan Liu and Steven X. Hou ()
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Shree Ram Singh: The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health
Xiankun Zeng: The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health
Jiangsha Zhao: The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health
Ying Liu: The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health
Gerald Hou: The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health
Hanhan Liu: The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health
Steven X. Hou: The Basic Research Laboratory, National Cancer Institute at Frederick, National Institutes of Health

Nature, 2016, vol. 538, issue 7623, 109-113

Abstract: Attenuating the lipolysis pathway in Drosophila melanogaster by modulation of the COP1–Arf1 signalling complex induced necrosis in stem cells and led to their engulfment by differentiated cells.

Date: 2016
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DOI: 10.1038/nature19788

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