Atomic structure of the entire mammalian mitochondrial complex I

Karol Fiedorczuk, James A. Letts, Gianluca Degliesposti, Karol Kaszuba, Mark Skehel and Leonid A. Sazanov ()
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Karol Fiedorczuk: Institute of Science and Technology Austria
James A. Letts: Institute of Science and Technology Austria
Gianluca Degliesposti: MRC Laboratory of Molecular Biology
Karol Kaszuba: Institute of Science and Technology Austria
Mark Skehel: MRC Laboratory of Molecular Biology
Leonid A. Sazanov: Institute of Science and Technology Austria

Nature, 2016, vol. 538, issue 7625, 406-410

Abstract: The atomic structure of ovine mitochondrial complex I is solved at 3.9 Å resolution, revealing that supernumerary subunits stabilize the complex and providing insight into the molecular basis of its function and regulation.

Date: 2016
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DOI: 10.1038/nature19794

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