Identification of an atypical monocyte and committed progenitor involved in fibrosis

Takashi Satoh, Katsuhiro Nakagawa, Fuminori Sugihara, Ryusuke Kuwahara, Motooki Ashihara, Fumihiro Yamane, Yosuke Minowa, Kiyoharu Fukushima, Isao Ebina, Yoshichika Yoshioka, Atsushi Kumanogoh and Shizuo Akira ()
Additional contact information
Takashi Satoh: Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University
Katsuhiro Nakagawa: Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University
Fuminori Sugihara: Laboratory of Biofunctional Imaging, World Premier Institute Immunology Frontier Research Center, Osaka University
Ryusuke Kuwahara: Research Center for Ultra-high Voltage Electron Microscopy, Osaka University
Motooki Ashihara: Chugai Pharmaceutical Co.
Fumihiro Yamane: Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University
Yosuke Minowa: Chugai Pharmaceutical Co.
Kiyoharu Fukushima: Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University
Isao Ebina: Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University
Yoshichika Yoshioka: Laboratory of Biofunctional Imaging, World Premier Institute Immunology Frontier Research Center, Osaka University
Atsushi Kumanogoh: Core Research for Evolutional Science and Technology, Japan Agency for Medical Research and Development
Shizuo Akira: Laboratory of Host Defense, World Premier Institute Immunology Frontier Research Center, Osaka University

Nature, 2017, vol. 541, issue 7635, 96-101

Abstract: An atypical monocyte with partial granulocyte characteristics is identified and shown to be critical for the development of fibrosis.

Date: 2017
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DOI: 10.1038/nature20611

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