Hypoxia induces heart regeneration in adult mice

Yuji Nakada, Diana C. Canseco, SuWannee Thet, Salim Abdisalaam, Aroumougame Asaithamby, Celio X. Santos, Ajay M. Shah, Hua Zhang, James E. Faber, Michael T. Kinter, Luke I. Szweda, Chao Xing, Zeping Hu, Ralph J. Deberardinis, Gabriele Schiattarella, Joseph A. Hill, Orhan Oz, Zhigang Lu, Cheng Cheng Zhang, Wataru Kimura () and Hesham A. Sadek ()
Additional contact information
Yuji Nakada: University of Texas Southwestern Medical Center
Diana C. Canseco: University of Texas Southwestern Medical Center
SuWannee Thet: University of Texas Southwestern Medical Center
Salim Abdisalaam: University of Texas Southwestern Medical Center
Aroumougame Asaithamby: University of Texas Southwestern Medical Center
Celio X. Santos: King’s College London BHF Centre of Research Excellence, Faculty of Medicine, James Black Centre
Ajay M. Shah: King’s College London BHF Centre of Research Excellence, Faculty of Medicine, James Black Centre
Hua Zhang: McAllister Heart Institute, the University of North Carolina
James E. Faber: McAllister Heart Institute, the University of North Carolina
Michael T. Kinter: Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation
Luke I. Szweda: Free Radical Biology and Aging Research Program, Oklahoma Medical Research Foundation
Chao Xing: McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center
Zeping Hu: Children’s Medical Center Research Institute at UT Southwestern Medical Center
Ralph J. Deberardinis: Children’s Medical Center Research Institute at UT Southwestern Medical Center
Gabriele Schiattarella: University of Texas Southwestern Medical Center
Joseph A. Hill: University of Texas Southwestern Medical Center
Orhan Oz: University of Texas Southwestern Medical Center
Zhigang Lu: University of Texas Southwestern Medical Center
Cheng Cheng Zhang: University of Texas Southwestern Medical Center
Wataru Kimura: University of Texas Southwestern Medical Center
Hesham A. Sadek: University of Texas Southwestern Medical Center

Nature, 2017, vol. 541, issue 7636, 222-227

Abstract: A pathway triggered by chronic severe hypoxia boosts regeneration of injured hearts in adult mice.

Date: 2017
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DOI: 10.1038/nature20173

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