Variable chromatin structure revealed by in situ spatially correlated DNA cleavage mapping

Viviana I. Risca, Sarah K. Denny, Aaron F. Straight and William J. Greenleaf ()
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Viviana I. Risca: Stanford University School of Medicine
Sarah K. Denny: Biophysics Program, Stanford University
Aaron F. Straight: Stanford University School of Medicine
William J. Greenleaf: Stanford University School of Medicine

Nature, 2017, vol. 541, issue 7636, 237-241

Abstract: The first genome-wide map of human chromatin conformation at the 1–3 nucleosome (50–500 base pair) scale, obtained using ionizing radiation-induced spatially correlated cleavage of DNA with sequencing (RICC-seq), which identifies spatially proximal DNA–DNA contacts.

Date: 2017
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DOI: 10.1038/nature20781

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