Valine starvation leads to a hungry niche
R. Grant Rowe and
George Q. Daley ()
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R. Grant Rowe: Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
George Q. Daley: Boston Children's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.
Nature, 2017, vol. 541, issue 7636, 166-167
Abstract:
The haematopoietic stem cells that rejuvenate blood depend on a dietary source of the amino acid valine — a finding that has been exploited to reduce the toxicity of bone-marrow transplantation in mice.
Date: 2017
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DOI: 10.1038/nature21106
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