Structural basis of co-translational quality control by ArfA and RF2 bound to ribosome

Fuxing Zeng, Yanbo Chen, Jonathan Remis, Mrinal Shekhar, James C. Phillips, Emad Tajkhorshid and Hong Jin ()
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Fuxing Zeng: University of Illinois at Urbana-Champaign
Yanbo Chen: University of Illinois at Urbana-Champaign
Jonathan Remis: Northwestern University
Mrinal Shekhar: Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign
James C. Phillips: Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign
Emad Tajkhorshid: University of Illinois at Urbana-Champaign
Hong Jin: University of Illinois at Urbana-Champaign

Nature, 2017, vol. 541, issue 7638, 554-557

Abstract: The structure of the bacterial ribosome in complex with the ArfA and the release factor RF2 shows how ArfA recruits RF2 to terminate translation of messenger RNAs that lack a stop codon in the ribosome.

Date: 2017
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DOI: 10.1038/nature21053

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