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Molecular mechanism for the regulation of yeast separase by securin

Shukun Luo and Liang Tong ()
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Shukun Luo: Columbia University
Liang Tong: Columbia University

Nature, 2017, vol. 542, issue 7640, 255-259

Abstract: The crystal structure of yeast separase in complex with its inhibitor securin sheds light on the mechanism of inhibition, in which securin inhibits separase by inserting a short segment into the active site.

Date: 2017
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DOI: 10.1038/nature21061

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