Feedback control of AHR signalling regulates intestinal immunity

Chris Schiering, Emma Wincent, Amina Metidji, Andrea Iseppon, Ying Li, Alexandre J. Potocnik, Sara Omenetti, Colin J. Henderson, C. Roland Wolf, Daniel W. Nebert and Brigitta Stockinger ()
Additional contact information
Chris Schiering: The Francis Crick Institute
Emma Wincent: Swedish Toxicology Sciences Research Center
Amina Metidji: The Francis Crick Institute
Andrea Iseppon: The Francis Crick Institute
Ying Li: The Francis Crick Institute
Alexandre J. Potocnik: Institute of Immunology and Infection Research, The University of Edinburgh
Sara Omenetti: The Francis Crick Institute
Colin J. Henderson: Dundee University School of Medicine
C. Roland Wolf: Dundee University School of Medicine
Daniel W. Nebert: University of Cincinnati
Brigitta Stockinger: The Francis Crick Institute

Nature, 2017, vol. 542, issue 7640, 242-245

Abstract: Cytochrome P4501 enzymes have a role in the regulation of aryl hydrocarbon receptor ligand levels in the gut, affecting innate lymphoid and TH17 cell responses.

Date: 2017
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DOI: 10.1038/nature21080

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